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The cortical atrophy leads to compensatory dilation of the cerebral ventricles - hydrocephalus ex vacuo 
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MANSVELT, JAN VAN. Pick's disease. A syndrome of lobar cerebral atrophy, its clinico-anatomical and histopathological types. [S.l.], [s.n.], 1954. Groot 8vo, pp. XII, 312. Ingenaaid.

HIV enceph - cerebral atrophy.jpg
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Alzheimer's disease leads to cerebral atrophy, the external surface of the brain with widened sulci and narrowed gyri, mostly over the frontal and parietal

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Volume rendering image illustrating cerebral atrophy in the advanced alzheiemr's disease brain. Notably the widening of the crotical sulci indicative of the process of neuronal

atrophy.JPG
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